Protein Purification
Bio Rad Laboratories COLUMN AMINEX HPX-42A
Columns, Carbohydrate Analysis; Bio-Rad; Aminex; HPX-42A; 300 x 7.8mm; Temperature: 85 deg.C; Flow rate: 0.6mL/min
Abcam Probenecid, ABC-transporter inhibitor, 1G
MW 285.36 Da, Purity >98%. ABC-transporter inhibitor. Competitive MRP1 blocker. Pannexin channel blocker (IC₅₀ = 150 μM). Can be used to block the efflux of intracellular dyes and indicators.
The product is subject to the following: Abcam Restricted Use Statement
WELCH MATERIALS INC DEAE TanroseTM 6FF, 100mL/bottle
Name: DEAE Tanrose 6FF, specification: 100mL, property: weak anion exchange, bead structure: 6% agarose, mean particle size and range: 90μm, 45-165 μm,ligand density: 110-1600 μmol Cl-/mL, functional group: diethylaminoethyl, flow rate: 50-300 cm/h, pH stability: 2-9(long term), storage condition: 20% ethanol, 4-30°C. Similar Products: DEAE Sepharose FF
Cayman Chemical GSK3 InhIbItr XI 1mg
A potent inhibitor of GSK3β (Ki = 25 nM); inhibits GSK3β in HEK293 cells (EC50 = 32 nM)
Genscript Corporation CD4/LEU3 His Rhesus macaque
CD4 also known as L3T4 T4 and W3/25 is an approximately 55 kDa type I transmembrane glycoprotein that is expressed predominantly on thymocytes and a subset of mature T lymphocytes It is a standard phenotype marker for the identification of T cell populations Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses In T-cells functions primarily as a coreceptor for MHC class II molecule peptide complex
Tosoh Bioscience LLC TSKGEL ODS-120T 4.6X250
Column, Reversed Phase Chromatography; Tosoh TSKgel ODS-120T; Media: Silica; Particle: 5 micrometer; Pore Size: 120 angstrom; 4.6mm I.D. x 25cm Length; Stainless Steel
Genscript Corporation CD96/TACTILEBiotin His Av
The receptors CD96 and TIGIT are expressed on the surface of T and natural killer (NK) cells and recent studies suggest both play important inhibitory roles in immune function CD96 has been shown to modulate immune cell activity in mice with Cd96-/- mice displaying hypersensitive NK-cell responses to immune challenge and significant tumor resistance The counterbalance between the putative inhibitory CD96 and TIGIT receptors and the activating receptor CD226 offers unique strategies for immuno-oncology drug development
Genscript Corporation CD8 alpha/CD8ABiotin His
CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I favoring lipid raft partitioning of TCR and inducing intracellular signaling CD8 alpha is also found on dendritic cells and rat macrophages but whether CD8 alpha enhances responses of a partner receptor like TCR to activate these cells is not known
Genscript Corporation EpCAM/TROP1Biotin His Avi
Epithelial Cellular Adhesion Molecule (EpCAM) also known as KS1/4 gp40 GA733-2 17-1A and TROP 1 is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF like repeats a 23 aa transmembrane segment and a 26 aa cytoplasmic domain
Genscript Corporation MSLN/Mesothelin298-600 His
Mesothelin also known as MSLN is a protein that in humans is encoded by the MSLN gene Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF)
STEMCELL Technologies EasySep™ Mouse Neutrophil Enrichment Kit, For processing: 1 x 10^9 cells
The EasySep™ Mouse Neutrophil Enrichment Kit is designed to isolate neutrophils from single-cell suspensions of bone marrow or other tissues by negative selection. Unwanted cells are targeted for removal with biotinylated antibodies that are directed against non-neutrophils. Labeled cells are then recognized by Tetrameric Antibody Complexes that are directed against biotin and dextran. These cells are bound to magnetic particles and separated using an EasySep™ magnet without the use of columns. Desired cells are poured off into a new tube.
Tosoh Bioscience LLC TSKGEL ODS-80TS 2X150
Column, Reversed Phase Chromatography; Tosoh TSKgel ODS-80Ts; Media: Silica; Particle: 5 micrometer; Pore Size: 80 angstrom; 2mm I.D. x 15cm Length; Mini-Bore
Abcam (+)-Nutlin-3, p53-MDM2 binding inhibitor, 10MG
MW 581.5 Da, Purity >98%. p53-MDM2 binding inhibitor (IC₅₀ = 13 μM). Less potent enantiomer of (-)-Nutlin-3 (Asc-4428
The product is subject to the following: Abcam Restricted Use Statement
Abcam (-)-Nutlin-3, p53-MDM2 binding inhibitor, 5MG
MW 581.5 Da, Purity >98%. Potent p53-MDM2 binding inhibitor (IC50 = 90 nM). Enantiomer of (+)-Nutlin-3 (ab144426). Shows antiproliferative effects (IC50 values are 2.2 and 1.3 µM for human skin and murine fibroblasts respectively). Shows antitumor effects *in vivo.* Orally active.
The product is subject to the following: Abcam Restricted Use Statement